Title : Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450.

Pub. Date : 2014 May

PMID : 24553381






1 Functional Relationships(s)
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1 The results revealed that CYP1A2, CYP2B6, and CYP3A4 were induced (>2.0-fold) by omeprazole, phenobarbital, and rifampicin, respectively, in all the hepatocyte lots tested at enzyme activity level (23 lots) and mRNA level (8 lots). Omeprazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens