Title : TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.

Pub. Date : 2014 Feb 13

PMID : 24525731






1 Functional Relationships(s)
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1 Irinotecan, another chemotherapeutic agent to induce DNA damaging used to treat patients with advanced gastric cancer that progressed on cisplatin, was found to inhibit the expression of XRCC1 effectively, and leading to an increase in the sensitivity of resistant cells to cisplatin. Irinotecan X-ray repair cross complementing 1 Homo sapiens