Title : Short time exposure to hydrogen peroxide induces sustained glutathione export from cultured neurons.

Pub. Date : 2014 May

PMID : 24524999






2 Functional Relationships(s)
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1 The peroxide-induced extracellular GSH accumulation from neurons was lowered by 70% in the presence of MK571, an inhibitor of multidrug resistance protein (Mrp) 1. Glutathione ATP binding cassette subfamily C member 1 Homo sapiens
2 These data demonstrate that just a short exposure of viable cerebellar granule neurons to micromolar concentrations of hydrogen peroxide stimulates a prolonged Mrp1-mediated export of cellular GSH. Glutathione ATP binding cassette subfamily C member 1 Homo sapiens