Title : Pharmacological AMP kinase activators target the nucleolar organization and control cell proliferation.

Pub. Date : 2014

PMID : 24498249






2 Functional Relationships(s)
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1 AIMS: Phenformin, resveratrol and AICAR stimulate the energy sensor 5"-AMP activated kinase (AMPK) and inhibit the first step of ribosome biogenesis, de novo RNA synthesis in nucleoli. Phenformin protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 AIMS: Phenformin, resveratrol and AICAR stimulate the energy sensor 5"-AMP activated kinase (AMPK) and inhibit the first step of ribosome biogenesis, de novo RNA synthesis in nucleoli. Phenformin protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens