Title : The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics.

Pub. Date : 2013 Nov-Dec

PMID : 24492341






3 Functional Relationships(s)
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1 Segregation of antibody and FcRn from endosomes in tubulovesicular transport carriers (TCs) into the recycling pathway can also be observed in live cells, and the extent of IL-6 association with TCs correlates with increasing affinity of the antibody:IL-6 interaction at acidic pH. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide interleukin 6 Homo sapiens
2 Segregation of antibody and FcRn from endosomes in tubulovesicular transport carriers (TCs) into the recycling pathway can also be observed in live cells, and the extent of IL-6 association with TCs correlates with increasing affinity of the antibody:IL-6 interaction at acidic pH. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide interleukin 6 Homo sapiens
3 Segregation of antibody and FcRn from endosomes in tubulovesicular transport carriers (TCs) into the recycling pathway can also be observed in live cells, and the extent of IL-6 association with TCs correlates with increasing affinity of the antibody:IL-6 interaction at acidic pH. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide interleukin 6 Homo sapiens