Title : A unique co-culture model for fundamental and applied studies of human fetoplacental steroidogenesis and interference by environmental chemicals.

Pub. Date : 2014 Apr

PMID : 24486430






2 Functional Relationships(s)
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Protein Name
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1 Atrazine and prochloraz had cell-type specific effects on CYP19 activity and estrogen production in co-culture. Atrazine cytochrome P450 family 19 subfamily A member 1 Homo sapiens
2 Atrazine induced CYP19 activity and estrogen production in H295R cells only, but did not affect overall estrogen production in co-culture, whereas prochloraz inhibited CYP19 activity exclusively in BeWo cells and reduced estrogen production in co-culture by almost 90%. Atrazine cytochrome P450 family 19 subfamily A member 1 Homo sapiens