Title : Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide.

Pub. Date : 2014 Feb

PMID : 24471407






1 Functional Relationships(s)
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1 Pioglitazone reduced visceral hypersensitivity and defecation frequency, increased nociceptive thresholds, NO production and iNOS activity and shifted stool form towards hard stools in D-IBS rats. Pioglitazone nitric oxide synthase 2 Rattus norvegicus