Title : Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population.

Pub. Date : 2014 May

PMID : 24469730






6 Functional Relationships(s)
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1 Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
2 Single nucleotide polymorphisms (SNPs) of the adenosine triphosphate-binding cassette B1 (ABCB1) gene have been demonstrated to be related to steroid-induced ONFH in small sample sizes of Japanese kidney failure and Chinese systemic lupus erythematosus patients. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
3 Single nucleotide polymorphisms (SNPs) of the adenosine triphosphate-binding cassette B1 (ABCB1) gene have been demonstrated to be related to steroid-induced ONFH in small sample sizes of Japanese kidney failure and Chinese systemic lupus erythematosus patients. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
4 However, there are obvious controversial results in the relationship of ABCB1 gene polymorphisms with steroid-induced ONFH. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
5 The aim of this study was to validate the genetic association of ABCB1 polymorphisms with the risk for steroid-induced ONFH in a large cohort of Chinese population. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
6 These findings suggested that rs1045642 SNP of ABCB1 may be associated with the risk of steroid-induced ONFH. Steroids ATP binding cassette subfamily B member 1 Homo sapiens