Title : Characterizing the effect of cytochrome P450 (CYP) 2C8, CYP2C9, and CYP2D6 genetic polymorphisms on stereoselective N-demethylation of fluoxetine.

Pub. Date : 2014 Mar

PMID : 24464553






1 Functional Relationships(s)
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1 Five CYP2C9 variants and CYP2D6.1 exhibited significantly stereoselective kinetic profiles prior to R-FLX, and CYP2C8.3 showed a slight stereoselectivity. r-flx cytochrome P450 family 2 subfamily C member 9 Homo sapiens