Title : Gβγ interacts with mTOR and promotes its activation.

Pub. Date : 2014 Feb 7

PMID : 24462769






1 Functional Relationships(s)
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1 In addition, chronic treatment with rapamycin, a condition known to interfere with assembly of mTORC2, reduces the interaction between Gbetagamma and mTOR and the phosphorylation of AKT; whereas overexpression of Galphai interfered with the effect of Gbetagamma as promoter of p70S6K and AKT phosphorylation. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens