Pub. Date : 2013 Oct-Dec
PMID : 24457404
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We aimed to assess the changes in PAI-1 levels in PCOS during treatment with metformin and during weight loss. | Metformin | serpin family E member 1 | Homo sapiens |
| 2 | RESULTS: In normal weight women, treatment with metformin reduced the body mass index (BMI) and circulating androgens, improved markers of IR and lowered PAI-1 levels. | Metformin | serpin family E member 1 | Homo sapiens |
| 3 | CONCLUSIONS: Metformin and sibutramine, but not orlistat, reduce PAI-1 levels in PCOS. | Metformin | serpin family E member 1 | Homo sapiens |