Title : Disparate effects of pharmacotherapy on plasma plasminogen activator inhibitor-1 levels in women with the polycystic ovary syndrome.

Pub. Date : 2013 Oct-Dec

PMID : 24457404






3 Functional Relationships(s)
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1 We aimed to assess the changes in PAI-1 levels in PCOS during treatment with metformin and during weight loss. Metformin serpin family E member 1 Homo sapiens
2 RESULTS: In normal weight women, treatment with metformin reduced the body mass index (BMI) and circulating androgens, improved markers of IR and lowered PAI-1 levels. Metformin serpin family E member 1 Homo sapiens
3 CONCLUSIONS: Metformin and sibutramine, but not orlistat, reduce PAI-1 levels in PCOS. Metformin serpin family E member 1 Homo sapiens