Title : Betaine supplementation protects against high-fructose-induced renal injury in rats.

Pub. Date : 2014 Mar

PMID : 24456735






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1 These protective effects were relevant to the anti-inflammatory action by inhibiting the production of inflammatory cytokines including interleukin (IL)-1beta, IL-18, IL-6 and tumor necrosis factor-alpha in renal tissue of high-fructose-fed rat, being more likely to suppress renal NOD-like receptor superfamily, pyrin domain containing 3 inflammasome activation than nuclear factor kappaB activation. Fructose interleukin 6 Rattus norvegicus