Title : LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

Pub. Date : 2014 Mar 7

PMID : 24451380






2 Functional Relationships(s)
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1 Moreover, we demonstrate that the peculiar interaction of LT175 with PPARgamma affected the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1), fundamentals for the PPARgamma-mediated adipogenic program. Cyclic AMP peroxisome proliferator activated receptor gamma Mus musculus
2 Moreover, we demonstrate that the peculiar interaction of LT175 with PPARgamma affected the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1 (NCoR1), fundamentals for the PPARgamma-mediated adipogenic program. Cyclic AMP peroxisome proliferator activated receptor gamma Mus musculus