Pub. Date : 2013 Nov 29
PMID : 24427810
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Two cysteines, Cys23 and Cys45, in the A-domain of HMGB1 form a disulfide bond under oxidative conditions. | Disulfides | high mobility group box 1 | Homo sapiens |
2 | The reorientation of the Phe38 ring by the disulfide bond in the A-domain may explain the reduced HMGB1 binding affinity towards cisplatinated DNA. | Disulfides | high mobility group box 1 | Homo sapiens |