Title : Acute alcohol intoxication impairs methicillin-resistant Staphylococcus aureus clearance in the lung by impeding epithelial production of Reg3γ.

Pub. Date : 2014 Apr

PMID : 24421048






3 Functional Relationships(s)
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1 An increased pulmonary bacterial burden was observed in alcohol-intoxicated mice at 16 and 24 h and was associated with decreased levels of interleukin 6 (IL-6). Alcohols interleukin 6 Mus musculus
2 An increased pulmonary bacterial burden was observed in alcohol-intoxicated mice at 16 and 24 h and was associated with decreased levels of interleukin 6 (IL-6). Alcohols interleukin 6 Mus musculus
3 Therefore, acute alcohol intoxication leads to decreased MRSA clearance in part by inhibiting IL-6/STAT3 induction of the antimicrobial protein Reg3gamma in the pulmonary epithelium. Alcohols interleukin 6 Mus musculus