Title : Synthesis and biological evaluation of novel tricyclic oxazine and oxazepine fused quinazolines. Part 1: erlotinib analogs.

Pub. Date : 2014 Feb 1

PMID : 24411123






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compounds 1b-1f, 1h effectively inhibited the in vitro kinase activity of EGFR and HER2 with similar efficacy as erlotinib and gefitinib. Hydrogen epidermal growth factor receptor Homo sapiens