Pub. Date : 2014
PMID : 24406279
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | On the other hand, in order to explain the differences in the clinical response to CBZ, genetic polymorphisms in phase I (CYP3A4, CYP3A5 and EPHX1) and phase II (UGT2B7) metabolising enzymes have been assessed; additionally, the influence of transporters (ABCB1 and ABCC2), receptors (PXR) and other drug targets (voltage- gated Na+ channels) in CBZ clinical response has been evaluated. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |