Title : Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication.

Pub. Date : 2014 Feb 1

PMID : 24405813






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Molecular modeling of these alkaloids docked to a homology model of Pgp was employed to optimize ligand-protein interactions and design analogues with increased affinity to Pgp. Alkaloids ATP binding cassette subfamily B member 1 Homo sapiens
2 Molecular modeling of these alkaloids docked to a homology model of Pgp was employed to optimize ligand-protein interactions and design analogues with increased affinity to Pgp. Alkaloids ATP binding cassette subfamily B member 1 Homo sapiens