Title : In vitro inhibition of human liver cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes by rose bengal: system-dependent effects on inhibitory potential.

Pub. Date : 2014 Jul

PMID : 24405273






1 Functional Relationships(s)
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1 To determine if a more physiologically-relevant test system could be protected from such an effect, rose bengal was evaluated as an inhibitor of CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 3A4/5 and UGT enzymes in CHH. Rose Bengal cytochrome P450 family 1 subfamily A member 2 Homo sapiens