Title : Inhibition of the leptin-induced activation of the p38 MAPK pathway contributes to the protective effects of naringin against high glucose-induced injury in H9c2 cardiac cells.

Pub. Date : 2014 Mar

PMID : 24399619






3 Functional Relationships(s)
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1 Inhibition of the leptin-induced activation of the p38 MAPK pathway contributes to the protective effects of naringin against high glucose-induced injury in H9c2 cardiac cells. naringin mitogen activated protein kinase 14 Rattus norvegicus
2 In this study, we demonstrate that naringin, a citrus flavonone, protects cardiomyoblasts (H9c2 cells) against high glucose (HG)-induced apoptosis by modulating the activation of the p38 MAPK pathway. naringin mitogen activated protein kinase 14 Rattus norvegicus
3 We investigated the hypothesis that naringin prevents HG-induced injury by inhibiting the leptin-induced activation of the p38 MAPK pathway in H9c2 cells. naringin mitogen activated protein kinase 14 Rattus norvegicus