Title : Exploring the effects of tert-butylhydroperoxide induced liver injury using proteomic approach.

Pub. Date : 2014 Feb 28

PMID : 24394546






3 Functional Relationships(s)
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1 t-BHP dose-dependent induction of cell apoptosis and stained liver sections relieved the acute rat liver injury were accompanied by sustained phosphorylation of JNK1/2 and p65. tert-Butylhydroperoxide mitogen-activated protein kinase 8 Homo sapiens
2 This study demonstrated that there was an increase in the cellular levels of ETFA in the t-BHP induction in viability and apoptosis via the activation of JNK1/2 and NFkappaB signaling modules. tert-Butylhydroperoxide mitogen-activated protein kinase 8 Homo sapiens
3 NAC administration and shRNA ETFA conferred resistance to t-BHP-increased ETFA and CHOP expression via IRE1-alpha/TRAF2 complex formation, activation of JNK1/2 and p50. tert-Butylhydroperoxide mitogen-activated protein kinase 8 Homo sapiens