Title : An ethinyl estradiol-levonorgestrel containing oral contraceptive does not alter cytochrome P4502C9 in vivo activity.

Pub. Date : 2014 Mar

PMID : 24368832






2 Functional Relationships(s)
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1 In the current study, we examined the phenotypic status of CYP2C9 using low-dose (125 mg) tolbutamide before and after oral contraceptive use in reproductive age women. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 The natural logarithm of tolbutamide C24, a metric for CYP2C9 phenotype, was found to be equivalent (within 80%-125% equivalency boundaries) before and after oral contraceptive use. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens