Title : Regulation of iron uptake in primary culture rat hepatocytes: the role of acute-phase cytokines.

Pub. Date : 2014 Apr

PMID : 24365882






2 Functional Relationships(s)
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1 This uptake was further enhanced in the presence of AP cytokines with a maximum iron uptake (481 +- 25.81 microg/g of protein) after concomitant administration of IL-6 + iron to cultured hepatocytes. Iron interleukin 6 Rattus norvegicus
2 In contrast, a decreased TfR1 level was detected by IL-6 and iron alone, whereas combination of iron and AP cytokines (mainly IL-6) abrogated the downregulation of TfR1. Iron interleukin 6 Rattus norvegicus