Title : Targeting the MET gene for the treatment of non-small-cell lung cancer.

Pub. Date : 2014 Feb

PMID : 24355409






2 Functional Relationships(s)
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1 Following the development of small molecules (gefitinib/erlotinib and crizotinib) able to reversibly inhibit the epidermal growth factor receptor (EGFR) and signaling pathways mediated by anaplastic lymphoma kinase (ALK), respectively, the MET signaling pathway has also been recognized as a potential target. Erlotinib Hydrochloride ALK receptor tyrosine kinase Homo sapiens
2 Following the development of small molecules (gefitinib/erlotinib and crizotinib) able to reversibly inhibit the epidermal growth factor receptor (EGFR) and signaling pathways mediated by anaplastic lymphoma kinase (ALK), respectively, the MET signaling pathway has also been recognized as a potential target. Erlotinib Hydrochloride ALK receptor tyrosine kinase Homo sapiens