Title : Postinjury hyperfibrinogenemia compromises efficacy of heparin-based venous thromboembolism prophylaxis.

Pub. Date : 2014 Jan

PMID : 24351527






4 Functional Relationships(s)
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1 RESULTS: In vitro studies revealed increased fibrinogen reversed the effects of heparin as measured by TEG. Heparin fibrinogen beta chain Homo sapiens
2 Moreover, there was a moderate inverse correlation between fibrinogen level and the effect of heparin (RF), which was significant on study days 1 and 3, implicating hyperfibrinogenemia in heparin resistance. Heparin fibrinogen beta chain Homo sapiens
3 Moreover, there was a moderate inverse correlation between fibrinogen level and the effect of heparin (RF), which was significant on study days 1 and 3, implicating hyperfibrinogenemia in heparin resistance. Heparin fibrinogen beta chain Homo sapiens
4 The preclinical and clinical relationships between fibrinogen levels and hypercoagulability implicate hyperfibrinogenemia as a potential factor in heparin resistance. Heparin fibrinogen beta chain Homo sapiens