Title : PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.

Pub. Date : 2013 Dec 12

PMID : 24336083






1 Functional Relationships(s)
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1 Indeed, knockdown of PATZ1 in p53-null osteosarcoma cells upregulates BAX expression and decreases survival of 5FU-treated cells, then suggesting an anti-apoptotic role of PATZ1 in p53-null cancer cells. Fluorouracil BCL2-associated X protein Mus musculus