Title : Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.

Pub. Date : 2014 Mar

PMID : 24333668






1 Functional Relationships(s)
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1 These data suggest that PKA/PDE-mediated cAMP signaling, integrated by RACK-1 to IFNAR2, may negatively regulate IFN signaling through SHP-2. Cyclic AMP protein tyrosine phosphatase non-receptor type 11 Homo sapiens