Title : Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages.

Pub. Date : 2012 Oct-Dec

PMID : 24331589






2 Functional Relationships(s)
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1 Although there may be multiple mechanisms by which ARBs ameliorate insulin resistance, for example, through effects on muscle or other tissues via the circulatory system, this is the first report demonstrating that a favorable effect of valsartan involves normalization of the interaction between adipocytes and macrophages. Valsartan insulin Homo sapiens
2 This mechanism of valsartan action holds promise for developing treatments for obesity-related insulin resistance. Valsartan insulin Homo sapiens