Title : Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1.

Pub. Date : 2014 Sep

PMID : 24327206






1 Functional Relationships(s)
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1 Ang II, ET-1 and EGF increased myocardial superoxide production (187 +- 9 %, 149 +- 8 % and 163.7 +- 6 % of control, respectively) and AG1478 inhibited these effects. Superoxides angiotensinogen Homo sapiens