Title : BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.

Pub. Date : 2013 Dec

PMID : 24322755






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Together, the results suggest that BIX induces autophagy-dependent cell death via EHMT2 dysfunction and intracellular ROS accumulation in breast and colon cancer cells, therefore EHMT2 inhibition can be an effective therapeutic strategy for cancer treatment. 2-(3,4-dihydroxyphenyl)-2-oxoethyl thiocyanate euchromatic histone lysine methyltransferase 2 Homo sapiens