Title : Prenatal buprenorphine exposure decreases neurogenesis in rats.

Pub. Date : 2014 Feb 10

PMID : 24321744






2 Functional Relationships(s)
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1 Results of parallel cell studies further demonstrated a negative impact of buprenorphine on cultured neurospheres, including proliferation, differentiation, BDNF expression and signaling, and PKA activity. Buprenorphine brain-derived neurotrophic factor Rattus norvegicus
2 Taken together, our results suggest that prenatal exposure to buprenorphine might result in depression-like phenotypes associated with impaired BDNF action and decreased neurogenesis in the developing brain of weanlings. Buprenorphine brain-derived neurotrophic factor Rattus norvegicus