Pub. Date : 2014 Jul
PMID : 24318462
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, our knowledge about the expression and function of KLF4 in the endothelial cells of BTB still remains unclear. | btb | Kruppel like factor 4 | Homo sapiens |
| 2 | In this study, we sought to investigate the role of KLF4 in regulation of BTB function as well as the potential molecular mechanisms. | btb | Kruppel like factor 4 | Homo sapiens |
| 3 | Short hairpin RNA targeting KLF4 impaired the integrity of BTB detected by trans-endothelial electric resistance assay, and meanwhile reduced the expression of ZO-1, occludin and claudin-5, demonstrated by quantitative RT-PCR, Western blot, and immunofluorescence assays. | btb | Kruppel like factor 4 | Homo sapiens |
| 4 | Depletion of KLF4 increased BTB permeability to small molecules detected by permeability assays. | btb | Kruppel like factor 4 | Homo sapiens |