Title : Trastuzumab and oxaliplatin exhibit a synergistic antitumor effect in HER2-postive gastric cancer cells.

Pub. Date : 2014 Mar

PMID : 24300914






3 Functional Relationships(s)
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1 In MTT assays, combination treatment with oxaliplatin and trastuzumab significantly decreased the concentration of oxaliplatin required to induce 50% growth inhibition in HER2-positive gastric cancer cells. Oxaliplatin erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 In MTT assays, combination treatment with oxaliplatin and trastuzumab significantly decreased the concentration of oxaliplatin required to induce 50% growth inhibition in HER2-positive gastric cancer cells. Oxaliplatin erb-b2 receptor tyrosine kinase 2 Homo sapiens
3 These findings suggest that trastuzumab synergizes the cytotoxic effect of oxaliplatin on HER2-positive gastric and breast cancer cells. Oxaliplatin erb-b2 receptor tyrosine kinase 2 Homo sapiens