Title : NQO1 involves in the imine bond reduction of sanguinarine and recombinant adeno-associated virus mediated NQO1 overexpression decreases sanguinarine-induced cytotoxicity in rat BRL cells.

Pub. Date : 2014 Feb 10

PMID : 24300172






1 Functional Relationships(s)
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1 These data illustrated that NQO1 involved in the imine bond reduction of sanguinarine and this was a less toxic metabolizing pathway than CYP1A1-metabolizing pathway. sanguinarine cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus