Pub. Date : 2014 Mar 1
PMID : 24277455
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Because WRN-deficient cells are known to be hypersensitive to camptothecins, we utilize trabectedin to block EWS-FLI1 activity, suppress WRN expression, and selectively sensitize Ewing sarcoma cells to the DNA-damaging effects of SN38. | Trabectedin | Fli-1 proto-oncogene, ETS transcription factor | Homo sapiens |