Title : Molecular dynamics and molecular docking studies on E166A point mutant, R274N/R276N double mutant, and E166A/R274N/R276N triple mutant forms of class A β-lactamases.

Pub. Date : 2014 Dec

PMID : 24261683






1 Functional Relationships(s)
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1 Molecular docking results indicate the mutation in class A beta-lactamases which decrease the binding affinity of Cefpirome and Ceftobiprole which are third and fifth generation Cephalosporins, respectively. Cephalosporins amyloid beta precursor protein Homo sapiens