Title : Preventive inositol hexaphosphate extracted from rice bran inhibits colorectal cancer through involvement of Wnt/β-catenin and COX-2 pathways.

Pub. Date : 2013

PMID : 24260743






3 Functional Relationships(s)
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1 Preventive inositol hexaphosphate extracted from rice bran inhibits colorectal cancer through involvement of Wnt/beta-catenin and COX-2 pathways. Phytic Acid catenin beta 1 Rattus norvegicus
2 Interestingly, the administration of IP6 had also markedly decreased beta-catenin and COX-2 in colon tumors. Phytic Acid catenin beta 1 Rattus norvegicus
3 Thus, the downregulation of beta-catenin and COX-2 could play a role in inhibiting the CRC development induced by IP6 and thereby act as a potent anticancer agent. Phytic Acid catenin beta 1 Rattus norvegicus