Title : The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation.

Pub. Date : 2014 Feb

PMID : 24249597






2 Functional Relationships(s)
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1 Individuals carrying the CYP3A4*22 T-variant allele have a lower tacrolimus dose requirement than individuals with the CYP3A4*22 CC genotype and this effect appears to be independent of CYP3A5 genotype status. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Individuals carrying the CYP3A4*22 T-variant allele have a lower tacrolimus dose requirement than individuals with the CYP3A4*22 CC genotype and this effect appears to be independent of CYP3A5 genotype status. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens