Title : Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2K(d) -specific CD8+ T cells.

Pub. Date : 2014 Jun 15

PMID : 24249003






2 Functional Relationships(s)
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1 Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2K(d) -specific CD8+ T cells. Cyclophosphamide histocompatibility 2, K1, K region Mus musculus
2 Importantly, the analysis of CD8+ T cells specific to P1A/H-2L(d) and P1E/H-2K(d) revealed that cyclophosphamide altered the P815-specific CD8 T repertoire by amplifying the response specific to the mutated P1E antigen. Cyclophosphamide histocompatibility 2, K1, K region Mus musculus