Pub. Date : 2014 Feb
PMID : 24194565
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Impaired hepatic clearance due to low-activity polymorphisms in human OATP1B1 may increase systemic exposure to SN-38, the active and toxic metabolite of the anticancer prodrug irinotecan. | Irinotecan | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
2 | Impaired hepatic clearance due to low-activity polymorphisms in human OATP1B1 may increase systemic exposure to SN-38, the active and toxic metabolite of the anticancer prodrug irinotecan. | Irinotecan | solute carrier organic anion transporter family member 1B1 | Homo sapiens |