Title : Increased nitric oxide bioavailability in adult GRK2 hemizygous mice protects against angiotensin II-induced hypertension.

Pub. Date : 2014 Feb

PMID : 24191280






1 Functional Relationships(s)
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1 AngII infusion also (1) increased GRK2 levels in WT but not in GRK2(+/-) vessels; (2) increased vasoconstrictor responses to phenylephrine in WT but not in GRK2(+/-) mice; and (3) decreased vasodilator responses to acetylcholine and vascular pAkt and eNOS levels more in WT than in GRK2(+/-) animals. Acetylcholine angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus