Title : Methylglyoxal, glyoxalases and the development of diabetic complications.

Pub. Date : 1994 Feb

PMID : 24190739






1 Functional Relationships(s)
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1 Aldose reductase inhibitors decrease the concentration of methylglyoxal in experimental diabetic rats to normal levels, aminoguanidine and L-arginine scavenge methylglyoxal; these effects may be involved in their prospective preventive therapy of diabetic complications. pimagedine aldo-keto reductase family 1 member B1 Rattus norvegicus