Title : Wilms' tumor gene 1 enhances nutlin-3-induced apoptosis.

Pub. Date : 2014 Jan

PMID : 24190574






1 Functional Relationships(s)
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1 Collectively, these results suggest that WT1 potentiates nutlin-3-induced apoptosis by downregulating the expression of BCL-XL while upregulating that of BAK, which leads to the activation of an intrinsic apoptotic pathway. nutlin 3 BCL2 antagonist/killer 1 Homo sapiens