Pub. Date : 2014 Jul
PMID : 24172227
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Short-term exposure to oleandrin enhances responses to IL-8 by increasing cell surface IL-8 receptors. | oleandrin | C-X-C motif chemokine ligand 8 | Homo sapiens |
2 | Short-term exposure to oleandrin enhances responses to IL-8 by increasing cell surface IL-8 receptors. | oleandrin | C-X-C motif chemokine ligand 8 | Homo sapiens |
3 | Here, we studied the effects of the plant glycoside oleandrin on responses to IL-8 in a human monocytic cell line. | oleandrin | C-X-C motif chemokine ligand 8 | Homo sapiens |
4 | Pulse exposure to oleandrin increased expression of IL-8 receptors and chemotaxis, release of enzymes and activation of NF-kappaB, NFAT and AP-1 along with increased IL-8-mediated calcineurin activation, and wound healing. | oleandrin | C-X-C motif chemokine ligand 8 | Homo sapiens |
5 | Pulse exposure to oleandrin increased expression of IL-8 receptors and chemotaxis, release of enzymes and activation of NF-kappaB, NFAT and AP-1 along with increased IL-8-mediated calcineurin activation, and wound healing. | oleandrin | C-X-C motif chemokine ligand 8 | Homo sapiens |
6 | CONCLUSIONS AND IMPLICATIONS: Short-term (1 h; pulse) exposure to a toxic glycoside oleandrin, enhanced biological responses to IL-8 in monocytic cells, without cytoxicity. | oleandrin | C-X-C motif chemokine ligand 8 | Homo sapiens |