Pub. Date : 2013
PMID : 24167632
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To lower its effective dose, we precomplexed BMP-2 with the glycosaminoglycans (GAGs) dermatan sulfate (DS) or heparin (HP), prior to loading it into a hyaluronic acid (HA) hydrogel. | Dermatan Sulfate | bone morphogenetic protein 2 | Rattus norvegicus |
2 | To lower its effective dose, we precomplexed BMP-2 with the glycosaminoglycans (GAGs) dermatan sulfate (DS) or heparin (HP), prior to loading it into a hyaluronic acid (HA) hydrogel. | Dermatan Sulfate | bone morphogenetic protein 2 | Rattus norvegicus |
3 | Analysis of the kinetic interaction between BMP-2 and DS or HP showed that HP had approximately 10 times higher affinity for BMP-2 than DS, yet it equally stabilized the protein, as determined by alkaline phosphatase activity. | Dermatan Sulfate | bone morphogenetic protein 2 | Rattus norvegicus |