Protein Name bone morphogenetic protein 2
Organism Rattus norvegicus
Gene ID 29373
Gene Symbol

Bmp2

UniProt P49001 (BMP2_RAT)
Relationships Total Number of functionally related compound(s) : 356
Total Number of Articles : 472
Description

bone morphogenetic protein 2

Gene Summary

Enables growth factor activity; identical protein binding activity; and protein domain specific binding activity. Involved in several processes, including BMP signaling pathway; cellular response to mechanical stimulus; and response to retinoic acid. Acts upstream of or within positive regulation of neurogenesis and positive regulation of transcription by RNA polymerase II. Located in cytoplasm; extracellular space; and vesicle. Part of protein-containing complex. Human ortholog(s) of this gene implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Orthologous to human BMP2 (bone morphogenetic protein 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • bone morphogenetic protein 2
  • BMP-2
  • BMP-2A
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Properties