Title : The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation.

Pub. Date : 2014 Jun

PMID : 24165757






1 Functional Relationships(s)
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1 These results suggest that CYP2C9 has a role in the oxidation reactions of THT and indicate that it may be possible to predict the efficacy of Bu-based myeloablative conditioning before HSCT on the basis of CYP genotypes and Bu MRs. tetrahydrothiophene cytochrome P450 family 2 subfamily C member 9 Homo sapiens