Pub. Date : 2014 Jan 1
PMID : 24163073
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thioglycollate, used for macrophage elicitation, selectively upregulated PPARgamma and its target gene CD36 in peritoneal macrophages of both wild-type (WT) and Alox15(-/-) mice. | Thioglycolates | peroxisome proliferator activated receptor gamma | Mus musculus |
| 2 | The PPARgamma antagonist treatment also prevented L-NAME-induced hypertension in thioglycollate-injected Alox15(-/-) mice, indicating a PPARgamma-mediated effect in macrophage elicitation and the resultant hypertension. | Thioglycolates | peroxisome proliferator activated receptor gamma | Mus musculus |
| 3 | The PPARgamma antagonist treatment also prevented L-NAME-induced hypertension in thioglycollate-injected Alox15(-/-) mice, indicating a PPARgamma-mediated effect in macrophage elicitation and the resultant hypertension. | Thioglycolates | peroxisome proliferator activated receptor gamma | Mus musculus |