Title : Antagonism of brain insulin-like growth factor-1 receptors blocks estradiol effects on memory and levels of hippocampal synaptic proteins in ovariectomized rats.

Pub. Date : 2014 Mar

PMID : 24146138






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Estradiol treatment resulted in significantly increased hippocampal levels of postsynaptic density protein 95 (PSD-95), spinophilin, and synaptophysin. Estradiol discs large MAGUK scaffold protein 4 Rattus norvegicus
2 Estradiol treatment resulted in significantly increased hippocampal levels of postsynaptic density protein 95 (PSD-95), spinophilin, and synaptophysin. Estradiol discs large MAGUK scaffold protein 4 Rattus norvegicus
3 JB1 blocked the estradiol-induced increase of PSD-95 and spinophilin and attenuated the increase of synaptophysin. Estradiol discs large MAGUK scaffold protein 4 Rattus norvegicus