Title : The O-methylation of chrysin markedly improves its intestinal anti-inflammatory properties: Structure-activity relationships of flavones.

Pub. Date : 2013 Dec 15

PMID : 24134915






1 Functional Relationships(s)
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1 Flavone effects were assessed on soluble pro-inflammatory mediator (IL-8, IL-6, macrophage chemoattractant protein-1 (MCP-1), and cyclooxygenase-2 (COX-2)-derived PGE2) production and on nuclear factor (NF)-kappaB activation in 3d-confluent and 21d-differentiated Caco-2 cells stimulated with interleukin (IL)-1beta. flavone nuclear factor kappa B subunit 1 Homo sapiens